13.00 – 13.05

Tuula Kallunki, Danish Cancer Society: Introduction.

Session 1:

Homologous recombination in embryonal stem cells  

13.05 – 13.50

Nobel lecture: Oliver Smithies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA: Gene targeting approaches to complex genetic diseases (confirmed).

13.50 – 14.35

Nadia Rosenthal, Mouse Biology Unit, EMBL Monterotondo Outstation, Monterotondo, Rome, Italy: The mouse ascending: perspectives for human-disease models (confirmed).

14.35 – 15.00

Coffee

Session 2:

Knockout mice in biomedical research

15.00 - 15.30

Marc Caron, Department of Cell Biology, Duke University Medical Center, Durham, NC, USA: Local knockdown and targeted deletion of dopamine transporter genes in the brain (confirmed).

 15.30 – 16.00

Josef M. Penninger, Institute of Molecular Biotechnology of the Austrian Academy of Science, Vienna, Austria: From a little knock-out mouse to global understanding of bone metabolism(confirmed).

16.00 – 16.30

Stefan Karlsson, Molecular Medicine and Gene Therapy, Lunds University, Lund, Sweden: Gene targeting of hematopoiesis and gene therapy of hematopoietic stem cells (invited).

16.30 – 17.00

Speaker to be announced