Biomarker discovery and drug development in the omics era

09.30 – 10.30

Arrival and registration.

10.30 – 11.30

Session 1: Chemical genomics and drug development

Chair: Ole Nørregaard Jensen, SDU

Ulrik Gether, Institute of  Neuroscience and Pharmacology, University of Copenhagen: Pharmacogenomics of receptors and transporters in the nervous system.

Michael Sundström, Novo-Nordisk Proteome Centre, University of Copenhagen: Insights for the development of specific kinase inhibitors by targeted structural genomics.

11.30 – 12.30

Session 2: Plants, microbes and bioactive compounds

Chair: Uffe Hasbro Mortensen, DTU

Keynote Lecture: Birger Lindberg Møller, Institute for Plant Biology and Biotechnology, Faculty of Life Sciences, University of Copenhagen:  Screening for bioactive plant compounds in drug development.

12.30 – 13.15

Lunch

13.15 – 14.00

Exhibition

14.00 – 15.30

Session 3: Biomarkers for human diseases: From discovery to applications

Chair: Lars Haastrup Pedersen, Aalborg University

Anne-Christine Bay Jensen, Nordic Bioscience A/S, Herlev Hovedgade 207, Herlev: Neoepitopes: from discovery to application in bone and cartilage disorders.

Martin R. Larsen, Protein Research, Institute for Biochemistry and Molecular Biology, University of Southern Denmark: Proteomics approaches for identification of biomarkers in disease.

Børge Nordestgaard, Herlev Hospital and Copenhagen University: Biomarkers, genetics and risk factors in cardiovascular disesase.

15.30 – 16.00

Coffee break and exhibition

16.00 – 17.00

Session 4: Nanobioscience and drug delivery

Chair: Anders Vagnø Pedersen, DBS.

Yechezkel Barenholtz, Laboratory of Liposome and Membrane Research, Department of Biochemistry, Hebrew University-Hadassah Medical School, Jerusalem, Israel: Using PEGylated nano-liposomes to target tissue invaded by a foreign body.

Ole G. Mouritsen, MEMPHYS-Center for Biomembrane Physics, Department of Physics and Chemistry, University of Southern Denmark, Odense, Denmark: The impact of peptides on lipid membranes.

17.00 - 18.30

Session 5: Posters and exhibition

19.00 – 22.00

Banquet

09.00 – 10.30

Session 6: Structural biology and drug design

Chair: Thomas Schou, BioSys, DTU.

Poul Nissen, Department of Molecular Biology, University of Aarhus, Gustav Wieds Vej 10C, DK-8000 Aarhus, Denmark: The structural basis of ion transport by membrane pumps.

Jesper Wengel, Nucleic Acid Center, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark: New conformationally restricted DNA mimics.

Irina Kouskoumvekaki, Center for Biological Sequence Analysis, Technical University of Denmark: Chemoinformatics in drug discovery. 

10.30 – 11.00

 Coffee and exhibition

11.00 – 12.00

 Session 7: Structural biology and drug discovery

Chair: Steen Gammeltoft, Glostrup Hospital, University of Copenhagen, Denmark.

Keynote Lecture: Tom Blundell, Department of Biochemistry, University of Cambridge, United Kingdom: Genomes, structural biology and drug discovery: exploring biological and chemical space.

12.00 – 13.00

Lunch

13.00 – 14.00

Exhibition

14.00 – 15.30

Session 8: Antibody-based therapeutics.

Chair: Catharina Stenholm, Novozymes.

Jørgen Petersen, Genmab, Toldbodgade 33, 1253 Copenhagen K, Denmark: anti-CD20 antibodies in cancer treatment.

Anne Bondgaard Tolstrup, Antibody Expression, Symphogen, Elektrovej, Building 375, DK-2800 Lyngby, Denmark: Polyclonal antibodies in the treatment of cancer.

Jan Trøst Jørgensen, CMC Contrast, Abscion DTU, Diplomvej 376, Lyngby, Denmark: A model for drug-diagnostic co-development – Trastuzumab (Herceptin) and HercepTest.

15.30 – 16.00

Closure of the conference

Departure