Nobel Prize 2007 meeting

Gene Targeting in Mice

Date Thursday, July 10, 2008, 13:00 - 17:00
Location The Lundbeck Auditorium, Copenhagen Biocenter, Ole Maaløes vej 5, Copenhagen, Denmark
Organizers Tuula Kallunki, Danish Cancer Society and Steen Gammeltoft, Glostrup Hospital

Program

13.00 – 13.05

Tuula Kallunki, Danish Cancer Society: Welcome.

Session 1:

Homologous recombination in embryonal stem cells  

13.05 – 13.50

Nobel lecture: Oliver Smithies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA: Gene targeting approaches to complex genetic diseases.

13.50 – 14.30

Josef M. Penninger, Institute of Molecular Biotechnology of the Austrian Academy of Science, Vienna, Austria: From a little knock-out mouse to global understanding of bone metabolism.

14.30 – 15.00

Nadia Rosenthal, Mouse Biology Unit, EMBL Monterotondo Outstation, Monterotondo, Rome, Italy: The mouse ascending: perspectives for human-disease models.

15.00 – 15.30

Refreshments

Session 2:

Knockout mice in biomedical research

15.30 - 16.00

Marc Caron, Department of Cell Biology, Duke University Medical Center, Durham, NC, USA: Genetic Animal Models of CNS Disorders: Implications for therapies.

16.00 – 16.30

Henrik Semb, Stem Cell Center, Lund University, Lund, Sweden: Gene targeting in human embryonic stem cells: properties and applications.

16.30 – 17.00

Lars Bo Nielsen, Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark: Mouse models to study a new apolipoprotein (apoM) affecting lipoprotein metabolism and atherosclerosis.

17.00 – 17.30

Cord Brakebusch, Biotech Research and Innovation Centre, Copenhagen Biocenter, Ole Maaløes Vej 5, Copenhagen, Denmark: Function of Rho GTPases in skin.